Example Dual-Use Applications

 Hematology and Coagulation

Immediate Treatment Recommendations on Managing Bleeding, Trauma, and Coagulation

In space, there needs to be rapid diagnosis of cell counts and coagulation in the event of trauma, an accident, or the need to perform blood transfusions. This very same use parallels the need on Earth.

• For trauma

• Chronic blood cell conditions

• Tailored to reduce bleeding risk

• State-of-art AI and diagnostics working in tandem

Management of hematology disorders requires frequent in-person visits, multiple tests, and lack of personalized information, especially when it comes to associating the best treatment plan for you. Multiple $10s of billions are spent per year on treatment, therapies, and testing, and with rHEALTH, there is a better way that improves outcomes. Both clotting and blood cell disorders are time-intensive for patients and also current tools for their management outside the hospital are inadequate. Part of the reason is the hematocrit effect and another is the lack of accurate metering and mixing for existing commercially-available analyzers. The rHEALTH Awesome device provides performance that meets or exceeds central lab standards. Our hematology solutions include a FVIII test developed with support from Biogen and the NIH. It provides hemophilia A patients the ability to monitor their factor replacement levels. Our approach will allow these patients to monitor their clotting status anywhere and anytime, prior to sports and to identify optimal therapeutic regimens. Additional coagulation tests will be utilize to monitor heparins, INR, and direct Xa inhibitors. The rHEALTH technology has also been demonstrated, in conjunction with AstraZeneca, to be highly accurate in measurement of thrombocytopenia, a condition of low platelets which can arise from certain drugs, vaccines, or immunological conditions. In conjunction with BARDA’s DRIVe, we have developed a 15-parameter blood count test that allows the diversity of blood cell parameters to be measured accurately.